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cancer

Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition

We report the implementation of our in silico/synthesis pipeline by targeting the glutathione-dependent enzyme mPGES-1, a valuable macromolecular target in both cancer therapy and inflammation therapy. [...]

2021-09-10T11:28:32+02:00Maggio 7th, 2021|Pubblicazioni|

Development and Validation of a Serum Metabolomic Signature for Endometrial Cancer Screening in Postmenopausal Women

Key Points Question  Is combining the blood metabolomic signature of endometrial carcinoma with an ensemble machine learning algorithm a useful system for building a screening test [...]

2020-12-14T16:25:34+01:00Settembre 28th, 2020|Pubblicazioni|

Development and Validation of a Serum Metabolomic Signature for Endometrial Cancer Screening in Postmenopausal Women

Abstract Importance  Endometrial carcinoma (EC) is the most commonly diagnosed gynecologic cancer. Its early detection is advisable because 20% of women have advanced disease at the [...]

2021-04-26T12:51:37+02:00Settembre 28th, 2020|Pubblicazioni|

Trifolium Repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway

Abstract Some species of clover are reported to have beneficial effects in human diseases. However, little is known about the activity of the forage plant Trifolium [...]

2020-12-22T11:19:25+01:00Febbraio 6th, 2020|Pubblicazioni|

Modified drug combination may reduce risk of recurrence for some breast cancer patients

Masey Ross, M.D., and Charles Geyer, Jr., M.D. Credit: VCU Massey Cancer Center Oncologists at VCU Massey Cancer Center were invited to co-author [...]

2020-12-11T15:59:44+01:00Agosto 26th, 2019|Pubblicazioni|
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